The Division of Headquarters of Security and Safety Services (DHSSS) provides strategic leadership and oversight to the Security and Safety Services (SSS) in the United Nations Headquarters, Offices Away from Headquarters, Regional Commissions and Tribunals, through the provision of overall policy standardization and direction, operational guidance and technical support. It also serves as the focal point for advice to and consultation with other UN Departments, Missions, Agencies, Funds and Programmes, or other organizations in matters arising from, or affecting, SSS. The DHSSS Protection Coordination Unit manages all UN personal protection operations in a systematic and coordinated manner.

The Security and Safety Services ensure a safe and secure environment for staff, delegates and visitors at the United Nations Headquarters, Offices Away from Headquarters, Regional Commissions and Tribunals through the provision of:
- Pass and identification services
- Physical security services
- Explosive detection services
- Emergency response services and crisis management
- Safety services
- Inspection services
- Training services
Security and Safety Services operate at UN offices and facilities worldwide:
- United Nations (New York)
- United Nations Office at Geneva (UNOG)
- United Nations Office in Vienna (UNOV)
- United Nations Office in Nairobi (UNON)
- Economic Commission for Africa (ECA) Addis Ababa
- United Nations Economic Commission for Latin America and the Caribbean (ECLAC) Santiago
- United Nations Economic and Social Commission for Asia and the Pacific (ESCAP) Bangkok
- United Nations Economic and Social Commission for Western Asia (ESCWA) Beirut
- International Criminal Tribunal for Rwanda (ICTR)
- International Criminal Tribunal for Yugoslavia (ICTY)